Abstract: Sensitivity analysis of landslide parameters is the foundation of the landslide mechanism analysis and quantitative evaluation. The sensitivity coefficient method, the sensitivity function method and the orthogonal test method are the three most common methods in sensitivity analysis of landslide parameters. However, it is not clear whether the three methods would have the same results with the same input data. This paper takes the mechanical parameters of the slipzone of Xieliupo landslide as an example. Sensitivity analysis is made using the three different methods. Although the results are not the same, the Maxwell viscosity is identified as the most sensitive parameter by all the methods. The sensitivity coefficient method and the sensitivity function method are often limited to the cases with fewer parameters. The result by the orthogonal method is considered more reasonable for the slow moving landslide with multiple mechanical parameters.