Abstract: Due to complex geological, topographical and clearance conditions, a lot of high-fill airports with the characteristics of large volume of earthwork, complex filling materials, bad construction conditions, and toughly technical difficulty have appeared in mountainous area of southwest China. The purpose of this study is to analyze and summarize a typical case of a complex high-fill airport to provide references to other similar projects. In this paper, the reasons of tension cracks of filling slope in a high-fill airport in southwest China is analyzed, theoretical analysis is performed, and comprehensive treatment measures including construction of toe back pressure, geotextile material, anti-sliding pile, drainage system and draining holes are carried out. Monitoring data for more than 1.5 years after the treatment revealed that the deformation rate has reduled considerably, and that the treatment measures are reliable and effective. The study on deformation of slope, the method of theoretical calculation, and the treatment measures taken in the project will provide good reference for similar projects.