Abstract: To address the challenges posed by complex geological structures and the ambiguity inherent in single advanced prediction methods for deep-buried long diversion tunnels, this study presents a comprehensive advanced geological prediction technology based on multi-physics coupling, using the Yuxi section of the Central Yunnan Water Diversion Project as a case study. A comprehensive prediction system was constructed, characterized by long-distance macro-control via Tunnel Seismic Prediction(TSP), medium-distance water content identification via the Transient Electromagnetic Method(TEM), and short-distance fine characterization via Ground Penetrating Radar(GPR). By combining field data from typical construction sites such as Chenaju and Xiaopu, the geophysical response characteristics of mud and sand inrush, surrounding rock collapse, hidden karst, and structural water-rich zones were deeply analyzed. The results indicated that multi-source information fusion effectively eliminated detection blind spots. Specifically, the ratio of longitudinal to transverse wave velocity in TSP was sensitive to the mechanical state of the rock mass; the apparent resistivity in TEM was sensitive to the volume effect of water bodies; and GPR offered high resolution for near-field structural interfaces. Furthermore, disaster identification criteria based on multi-parameter constraints of wave velocity ratio, resistivity, and dielectric constant were established, i.e., "high wave velocity ratio+steep resistivity drop gradient" as a significant feature for identifying mud and sand inrush;"low velocity trough+disordered radar waveform" mainly corresponding to surrounding rock collapse; and"abrupt drop in wave velocity+strong diffraction wave" accurately corresponding to karst cavities. Engineering practice demonstrates that this comprehensive prediction system effectively achieves qualitative identification and precise localization of adverse geological bodies ahead of the tunnel face, significantly reducing the risk of water and mud inrush during the construction of deep-buried long tunnels.