Abstract: Under the comprehensive influences of tectonics, weathering, and acidification of acid rain, the rock mass along the Sichuan-Tibet Railway has extensive deep shattered zones. When the rock masses are excavated due to constructions, a series of deep and cataclastic rock slopes can be formed. These slopes are highly susceptible to collapse as well as overall instability, which is hard to be reinforced by the traditional safety netting system(SNS). This study proposes a new composite structure for slope protection, anchored flexible system, replacing bolts of SNS with prestressed anchor cables to constrain the surface displacement of the cataclastic rock slope while simultaneously stabilizing the slope body. Here, we conduct 1 ︰ 10 large-scale indoor model tests to explore the stress-strain characteristics, the coordinated loading mechanism, and the design method of the anchored flexible systems for cataclastic rock slope protection under heavy rainfall conditions. Model test reveals the coordinated loading between both prestressed anchor cables and nets in anchored flexible systems when the cataclastic rock slope deformation happens. The stress of the flexible nets has significant impacts on the working state of the prestressed anchor cable, and it can form an obvious re-tension, which should be fully taken into account in the design.