Abstract: Study of the regional stability and preliminary siting of the Anqing bridge are the important, basic work prior to the construction of the bridge. According to the requirements of the preliminary feasibility research, a study of remote sensing application aims to do the following works: (1) analysis of the alternative areas of the preliminary bridge site and the characteristics of its surrounding geological structures, understanding distribution of old and young faults in the area and analysis of their activity and evaluation ofthe regional stability by means of geological interpretation of the aerial and Landsat images; (2) analysis of evolution of the Changjiang River banks in the possible bridge site area and evaluation of its stability by using the aerial and Landsat images taken from 1950s to 1990s; and (3) analysis of engineering geological conditions of the preliminarily sited bridge areas, and put forward an optimum scheme.