Abstract: The geological hazard risk assessment is guiding significance to local disaster prevention and mitigation. Taking the Lancang River major hydropower engineering area as the research area, this study was based on the remote sensing interpretation and field surveys, and 9 impact factors(the elevation, slope, aspect, difference vegetation index(NDVI), distance to reservoir area, engineering geological rock group, fault zone density, average annual rainfall and peak acceleration of earthquake) were selected to evaluate the risk assessment based on weighted information model. Then, population density, hydropower station, road, land cover type and GDP are taken as the disaster bearing bodies to carry out vulnerability evaluation. Finally, the risk matrix of geological disaster is constructed, and the risk and vulnerability information is integrated to complete the risk evaluation of geological disaster. The evaluation results show that: the extremely high and high risk areas are mainly distributed in the vicinity of Wunonglong reservoir and its upstream hydropower station, and the regions with relatively intensive human activities on both sides of the downstream reservoir, while the medium risk areas are mainly distributed in the two sides of Wunonglong reservoir and the whole region of Wunonglong Toba Hydropower Station, scattered in the downstream. The low risk area is mainly distributed in the middle mountain valley. This study accurately evaluates the risk of geological hazards, which can provide scientific basis and technical guidance for the risk planning of geological hazards in Lancang River Basin.