Abstract: This paper is based on the latest remote sensing data of domestic gaogao-1 satellite(hereinafter referred to as GF-1) and collects ETM data in 1990, 2000 and 2010 to assist remote sensing interpretation. It finds out the distribution of major projects within 280 000 km² in the area adjacent to Southeast Asia. The major engineering activities in the study area are mainly hydropower(water conservancy) projects and transportation projects. Additionally there are also some mine engineering activities. The latest development and distribution of landslides disturbed by major projects are interpreted. There are as many as 1373 landslides that pose a direct threat to the living environment in the area. They include 625 induced by hydropower projects, 723 induced by traffic projects and 22 induced by mining projects. The correlation analysis with the geological environment shows that the major engineering disturbance landslides in the area are mostly developed on the sunny slope with frequent human activities at an altitude of 1000~3000 m and a slope of more than 25°, and the lithology is mainly soft rock, hard rock and engineering geological rock group with alternating soft and hard rocks.