Abstract: Shaking table test is an effective method to study the effect of seismic conditions on engineering practice at present. The selection of appropriate material ratio is the key to successful simulation of the prototype project. Based on Zhoujiawan Bridge of the Chongqing-Guizhou high-speed railway, the orthogonal test is used to study the rock material according to the separation similar design method and secondary refinement test. In this study, barite powder, quartz sand, iron powder, gypsum and rosin alcohol solution are used as proportion materials. The rock mass density, gravity acceleration and geometrical size are regarded as control indexes. By the method of extreme difference analysis, the influence of material contend of model test on simulating the main parameters of rock is studied. Then the second test for refining the analysis and determining the final material mix is conducted. The results show the follows. (1) The proportion of materials affects the main parameters such as deformation modulus, cohesion and internal friction angle on different emphasis and different degrees. (2) The similarity design method can be used to select the main parameters of each component in the similar test. The orthogonal test and the secondary refinement test can quickly and efficiently design and test the main parameters. Finally the parameters are obtained to meet the requirements of the model test.