Abstract: At present,the research on the internal force and deformation of landslide anti-slide pile under complex geological condition is still insufficient. In order to study the response of the anti-slide pile for Jiangdingya talus landslide,string wire stress gauges and the embedded strain gauges were installed in the anti-slide piles to monitor the stress and strain. A new calculation model based on monitoring data and a FE model in PLAXIS 3D were established for further study. The results show that the maximum stress of a single steel bar monitored is 112.5 MPa,which is much smaller than the design value,and the maximum stain is 34 με. The calculated model introduced in this paper is reliable and can be used on actual project. The bending moment calculated by the FE model is much smaller than the design value,but their change trends are consistent,which can prove that the monitored data are authentic and the FE model is reliable. The anti-slide piles are currently in a safe state and the treatment effect of Jiangdingya talus landslide is remarkable.