Abstract: The grillage supporting structure with anchor bars applied to loess slope is a new type of slope protection and reinforcement method. In this paper, the rational calculation models of the soil pressure, the grillage supporting structure and anchor bars are selected, and calculation elements of horizontal beams and vertical columns are emphasized. It also points out that beams and columns not only bear the uniform load in the beam cross section, but also bear the triangular or trapezoidal load passed from adjacent retaining plate. It is the superposition of the two components. Finally, a loess slope is designed and analyzed. The results show that this method is both safe and reliable and has a better economic applicability.