Abstract: Ground collapse is one of the major types of geological disasters and can have serious harm to the national economy and peoples lives and property and hamper the sustainable development in Guangzhou. The Information-value model and GIS are used for the fatalness appraisal study of ground collapse in downtown area of Guangzhou city. The appraisement indexes are conceived through choosing these factors such as fault, the stability of the earths crust, the quaternary sediment lithology and thickness, bedrock lithology, groundwater dynamics conditions, surface and underground intensity of human activities. ArcGIS software is applied involving in data collection, data management, data analysis and evaluation process, expressing. Finally, the fatalness classification chart of grade about ground collapse in Guangzhou is produced. The result tells us that there are five fatalness grades in main urban area, the most dangerous zone distribute in the south of Guang-hua basin, the more dangerous zone distribute the west-north of main urban, in Guang-cong fault or the intersection of subway, the basic stable grade zone distribute in the center of main urban area. The results show that the collapse hazard are caused by the interaction of the complicated nature environmental elements and the intense human activities.