Abstract: The section of No.212 highway in Gansu province is the most important composition of Gansus road network. Landslides and debris flows occur very often along this section. The area from Tanchang city to Wudou city is very famous for its active landslides and debris flows. This area is one of the major natural disaster areas in China. The highway goes through different geographical conditions, which causes great difference in styles and characteristics of landslides and debris flows. Based on filed observation and data collected, this paper explores the temporal and spatial variations of geomorphology and the relationship between landforms and landslides and debris flow. It provides guidelines for future design and construction of the highway.