Abstract: Engineering-geological zoning of plateau permafrost area by using remote sensing technique has great advantage. Qinghai-Tibeten plateau permafrost area is divided into three engineering-geological zones and ten sub-zones. The selecting Qingzang railway line is used as an example to illustrate the effectiveness of remote sensing interpretation in engineering-geological zoning of plateau permafrost area.The interpreted features of the Qingzang plateau permafrost area are systematically expounded.