Abstract: The slip of the landslide 102 frequently broke the Chuanzang Highway. Detailed field investigation of the landslide 102 and analysis of the factors causing the water-rock interaction in the landslide suggested that the water-rock interaction is intense and diverse in the area. Based on this result, the author studied the effect of water-rock interaction on the development and evolution of the landslide 102 on the Chuanzang Highway and then suggested that in prevention of the landslide a stress should be placed on the water-rock interaction.